VFC Ordering\u202f
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Enflonsia (clesrovimab) (105 mg\/0.7 mL syringes) will be available to order through the Vaccines for Children (VFC) program starting October 2, 2025. It will be available in one- and 10-dose packaging.
To add this formulation to your office’s list of vaccines, use the button below to complete a change request form. Providers interested in ordering clesrovimab on October 2 should complete the form by Friday, September 26, at 12 p.m. <\/p>\n\n\n\n
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Our team will review your request and reply with next steps. We recommend that providers that are affiliated or part of a system use the same vaccine presentations across sites to ensure standardization and help prevent administration errors. Please note that providers who add clesrovimab for the 2025-2026 season may need to order both nirsevimab and clesrovimab due to clesrovimab supply limitations.
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Dosage and Administration <\/strong><\/p>\n\n\n\n Clesrovimab is available in one dosage, 105 mg\/0.7 mL, administered as an intramuscular injection with a single-dose, pre-filled syringe.\u202f <\/p>\n\n\n\n RSV Immunization Product Indications <\/p>\n\n\n\n Eligible Patients<\/strong><\/p>\n\n\n\n Reporting<\/strong><\/p>\n\n\n\n All doses of clesrovimab administered in Philadelphia must be reported to PhilaVax.\u202f <\/p>\n\n\n\n <\/p>\n\n\n\n Clesrovimab Product Information <\/p>\n\n\n\n Storage and Handling <\/strong><\/p>\n\n\n\n Store refrigerated between 36\u00b0F to 46\u00b0F (2\u00b0C to 8\u00b0C) through the expiration date. \u202f If clesrovimab is administered:\u202f<\/p>\n\n\n\n <\/p>\n\n\n\n Additional Resources<\/strong>
Monoclonal Antibodies Available for Infant Vaccinations
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Clesrovimab is the second monoclonal antibody to be approved for use for the prevention of RSV LRTI in infants. \u202f<\/p>\n\n\n\n\n
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Clesrovimab may be kept at room temperature \u2013 68\u00b0F to 77\u00b0F (20\u00b0C to 25\u00b0C) \u2013 for a maximum of 48 hours.\u202fAfter removal from the refrigerator, clesrovimab must be used within 48 hours or discarded. <\/strong><\/p>\n\n\n\n
Reporting Adverse Events<\/strong><\/p>\n\n\n\n\n
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